This week I will embark upon a new journey to possibly help me in my fight. Low Dose Naltrexone.
It is approved through the FDA, Naltrexone, at 50 mg to aid in drug addiction. But Dr. Dr. Bihari, who discovered the benefits of MS patients taking this med in a low dose, hence the name, did not have the tens of millions of dollars to get it approved for MS treatment. But then again, keep in mind of all the deadly drugs in which ARE FDA approved?! Money talks. You know this.
Naltrexone, short for Naltrexone Hydrochloride, is an opiate antagonist. At a therapeutic dose of 50 mg per day, Naltrexone blocks the part of the brain that “feel” pleasure when a person uses alcohol or narcotics. When these areas of the brain are blocked, a person feels less need for “one more drink” or “one more hit.” The FDA approved the treatment of alcohol and opiate abuse, Naltrexone has recently shown great promise in the treatment of other medical conditions.
The use of low doses of naltrexone for the treatment of multiple sclerosis (MS) enjoys a worldwide following amongst MS patients. There is overwhelming anecdotal evidence, that in low doses naltrexone not only prevents relapses in MS but also reduces the progression of the disease. It is proposed that naltrexone acts by reducing apoptosis of oligodendrocytes. It does this by reducing inducible nitric oxide synthase activity. This results in a decrease in the formation of peroxynitrites, which in turn prevent the inhibition of the glutamate transporters. Thus, the excitatory neurotoxicity of glutamate on neuronal cells and oligodendrocytes via activation of the alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid class of glutamate receptor is prevented. It is considered “the cure”.
After extensive research and the help of fellow Swanker, Sheri, I had found two -of many- doctors who may prescribe it to me. One being in Pittsburgh. And, another in Mechanicsville, PA. Not all neuros and family doctors will prescribe it but many will..you just have to find the one who will. I was given that prescription today!
My closest friends are concerned, and I am truly grateful and moved to have a loyal circle who love me and worries for me, but I assure you, I have researched these doctors and this med. Just as I have everything in health, since May 2010. Bobby & Drew are witness to my mad scientist work, so they are hopeful the LDN is a positive experience for me and all for it.
Low Dose Naltrexone also known as “LDN” is a prescription drug that doctors are prescribing more and more to help many diseases go into remission. LDN is an inexpensive, low side effect, drug that has been in the news for its miraculous results in people with MS, fibromyalgia, many cancers, Lyme, psoriasis, children with autism, ALS, Alzheimer’s and many autoimmune diseases.
Dr. Bernard Bihari worked with LDN after it’s approval, but later then tried it in much smaller doses for his patients with MS and different types of cancer, which brought amazing results of complete remission.
Originally, Dr. Bihari gave the LDN to a friends daughter, who was diagnosed with MS, her progression and symptoms completely stopped. After some time of complete health, the girl even stopped taking the LDN, believing she never had MS and at that time, her symptoms returned. She went back on the LDN and her progression stopped once again. The dr then went on to prescribe to all his MS patients. Many others with MS, have had this med proven to them..through symptoms stopping and the positive, amazing change in their brains from MRI’s they returned for.
Dr. Bihari discovered that LDN has the ability to assist the immune system in fighting off disease and helping to build up the endorphins in the brain, among other important factors in helping the body heal.
As with anything in life, every person who may be dealt the same cards, makes the path they choose. Some stick with copaxone, some stick with the Swank or McDougal diet, some take the other meds the neuros push, and some take LDN. And then there are the ones who are not given definite answers yet try any and everything to get those answers.
Low Dose Naltrexone Has Helped Many People With MS.
CBS News did a full story on a woman named Ronnie Raymond who had lost her strength and balance 20 years before getting a prescription on LDN. She amazingly recovered her complete health after being on LDN. It is now recorded it has since helped many others with various diseases. You can find the story of Ronnie Raymond on CBS online.
More Than a Magic Bullet: Low Dose Naltrexone:
Less muscle spasms and pain
High sex drive
Less heat intolerance
Fatigue problems resolved
Healing of nerve damage
Repair in brain lesions
Restored immune system
Vivid dreams / disrupted sleep *can be used with benedryl or melatonin to aid this.*
High energy level
increased endorphin levels
Prevention and diminished expression of experimental autoimmune encephalomyelitis.
Halted progression of disease
Symptoms can return with levels of stress or high fat diet. & People on LDN must eat gluten free. In June 2010, gluten free was something I thought a part of Swank-finding to my relief I was mistaken. Believe me, eating gluten free is quite the feat. But, I will happily return to it.
LDN is proving stunningly positive results in repairing or reversing the damage with MS.
MS affects the areas of the brain and spinal cord known as the white matter. White matter cells carry signals between the grey matter areas, where the processing is done, and the rest of the body. More specifically, MS destroys oligodendrocytes which are the cells responsible for creating and maintaining a fatty layer, known as the myelin sheath, which helps the neurons carry electrical signals. MS results in a thinning or complete loss of myelin and, less frequently, the cutting (transection) of the neuron’s extensions or axons. When the myelin is lost, the neurons can no longer effectively conduct their electrical signals. The name multiple sclerosis refers to the scars (sclerosis – better known as plaques or lesions) in the white matter.
It’s been proposed that naltrexone acts by reducing the production of inducible nitric oxide synthase. This decreases the formation of peryoxynitrite molecules, which, in turn, prevents the inhibition of the glutamate transporters. No longer inhibited, the transporters move glutamate from the circulation preventing excess glutamate from accumulating. This prevents the excitatory neurotoxicity on neuronal cells and oligodendrocytes caused by excess glutamate. Reducing exitotoxicity reduces migroclial activation and it reduces apoptosis (programmed cell death) of the myelin-producing oligodendrocytes. This in turn, prevents destruction of the myelin sheath covering nerve fibers. Destruction of the myelin sheath is the underlying pathology in MS.
Most certainly, the closest thing to a ‘cure’ .. especially since there is no definitive test to determine if this person has MS.
Yes, my Radiological Isolated Syndrome diagnosis from Johns Hopkins can mean a handful of things, one being I may be in the early stages of MS, thankfully, I do have a list of things I ‘can’ deal with but I have not dealt with MANY of the symptoms that people with MS must face. I can sit in heat for hours for example. It does not affect me whatsoever.
I am doing great. Even though my MRI reads differently. Again, ‘treat the patient-not the MRI’ .. but, to see me, you would never guess I struggle with anything..let alone an incurable disease. And, so far, all I had struggled with in the past, has been repaired by my strict diet, attitude, exercise, yoga, massages, sleep, removal of mercury, and serious, disciplined supplements.
Granted, even though LDN is farily harmless, I am told LDN should send me to the hospital if I do not have this disease. When I used to take risks, my Mom would say, “I don’t know if you are the bravest person in the world or the dumbest..” — Her humor still comes into play for me. Thank god. & I wish, every day, I had her here to listen to her witty, witchy-poo wisdom about all of this..or anything for that matter. But I do not doubt she would be proud of me for my quest for answers. And, if you were living in limbo, without answers, and yet you feared you did in fact have this, would you not make the attempt to find answers or more importantly, try to halt any progression? I know I would.~Incurable means curable from within.~